Association of Serum Lactate with Outcome After Pediatric Out-of-Hospital Cardiac Arrest: A Secondary Analysis of the Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trial
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The authors aimed to investigate the association between serum lactate levels measured within 24 hours of return of spontaneous circulation (ROSC) and 12-month neurobehavioral outcomes and hospital mortality in pediatric patients following out-of-hospital cardiac arrest. Their analysis revealed that higher lactate levels were significantly correlated with unfavorable outcomes and increased odds of mortality, suggesting that lactate could serve as a valuable adjunct biomarker for early neuroprognostication in this population.
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