Resuscitation
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Diastolic blood pressure and end-tidal carbon dioxide during adult ICU cardiopulmonary resuscitation: association with return of spontaneous circulation

Jun 22, 2026

The authors aimed to evaluate the relationship between intra-arrest diastolic blood pressure (DBP) and end-tidal carbon dioxide (EtCO₂) levels with the return of spontaneous circulation (ROSC) during adult ICU cardiopulmonary resuscitation (CPR). Their findings indicate that both DBP and EtCO₂ are associated with ROSC, with DBP showing slightly better discrimination, although not statistically significant. The study suggests that these measures should be considered complementary indicators of physiological status during CPR rather than real-time predictors.

Association of Serum Lactate with Outcome After Pediatric Out-of-Hospital Cardiac Arrest: A Secondary Analysis of the Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trial

Jun 18, 2026

The authors aimed to investigate the association between serum lactate levels measured within 24 hours of return of spontaneous circulation (ROSC) and 12-month neurobehavioral outcomes and hospital mortality in pediatric patients following out-of-hospital cardiac arrest. Their analysis revealed that higher lactate levels were significantly correlated with unfavorable outcomes and increased odds of mortality, suggesting that lactate could serve as a valuable adjunct biomarker for early neuroprognostication in this population.

Comparison of Intraosseous Line Placement Location and Rates of Return of Spontaneous Circulation and Survival to Discharge Among Patients with Out-of-Hospital Cardiac Arrest

Jun 18, 2026

The authors aimed to compare the outcomes of return of spontaneous circulation (ROSC), survival to discharge, and neurological status in out-of-hospital cardiac arrest patients based on the location of intraosseous (IO) line placement, specifically humeral versus tibial. Their findings indicate that humeral IO placement is associated with significantly higher rates of ROSC and survival to discharge compared to tibial placement. The study suggests a need for further research to potentially inform protocol changes regarding optimal IO placement in cardiac arrest scenarios.

The AI dispatcher copilot: beyond cardiac arrest recognition to dynamic large language model-assisted Tele-CPR

Jun 18, 2026

The authors aim to explore the potential of a dynamic, large language model-assisted Tele-CPR system, termed the "AI dispatcher copilot," to enhance out-of-hospital cardiac arrest (OHCA) recognition and response. They propose that integrating multimodal AI capabilities can improve decision-making and reduce cognitive load for emergency dispatchers, ultimately aiming to improve clinical outcomes. The paper emphasizes the need for ethical governance and validation to ensure the effective implementation of this innovative approach in clinical practice.

Gentle limb fixation for a faster reliable heart rate obtained with pulse oximeter at birth

Jun 9, 2026

The authors aimed to investigate whether infant limb movement and gentle fixation after pulse oximeter application affect the time required to obtain a reliable heart rate (HR) reading in neonates during resuscitation. Their findings indicate that gentle limb fixation significantly reduces the time to achieve a reliable HR compared to limb movement, suggesting that this technique may enhance the timeliness of clinical assessments in neonatal care.

Long-term functional and quality of life outcomes for survivors of asystolic out-of-hospital cardiac arrest

Jun 9, 2026

The authors aimed to evaluate the long-term functional outcomes and health-related quality of life (HRQoL) for survivors of asystolic out-of-hospital cardiac arrest (OHCA). Their findings revealed that only one-third of the 12-month survivors achieved good functional recovery, with many experiencing significant disability and lower HRQoL compared to population norms. This highlights the challenges faced by OHCA survivors in terms of long-term health and quality of life.

Health Inequalities in Out-of-Hospital Cardiac Arrest Incidence and Bystander Cardiopulmonary Resuscitation Rates in England 2018-23

Jun 9, 2026

This study aims to identify high-risk areas in England for out-of-hospital cardiac arrest (OHCA) based on incidence rates and bystander cardiopulmonary resuscitation (BCPR) rates from 2018 to 2023. The authors found that high-risk areas are predominantly urban, deprived, and ethnically diverse, with lower rates of public access defibrillation, and they emphasize the need for targeted community interventions to address persistent health inequalities in OHCA outcomes. Despite some shifts in geographic patterns, the disparities in BCPR and survival rates have remained largely unchanged since 2015.

Prognostic Performance of Plasma and Urinary Biomarkers of Kidney Injury and Function After Out-Of-Hospital Cardiac Arrest

Jun 9, 2026

The authors aimed to determine whether kidney injury biomarkers could enhance the early prediction of patient-centered outcomes and acute kidney injury (AKI) following out-of-hospital cardiac arrest (OHCA), compared to serum creatinine (sCr). Their findings indicate that plasma and urinary biomarkers, particularly urinary NGAL, significantly outperformed sCr in predicting poor neurological recovery and AKI, suggesting that these biomarkers could improve risk stratification in clinical settings.

Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study

Jun 9, 2026

The authors aimed to investigate the characteristics, treatment patterns, and outcomes of patients experiencing cardiac arrest due to pulmonary embolism (PE) using a nationwide inpatient database in Japan from 2012 to 2024. They found that while the use of thrombolytic therapy decreased, the use of extracorporeal membrane oxygenation (ECMO) increased, leading to improved survival rates and favorable neurological outcomes over time, particularly among patients with hospital-acquired PE. Overall, the study highlights significant trends in treatment and outcomes for this high-mortality condition.

Refractory Ventricular Fibrillation in Out-of-Hospital Cardiac Arrest: Shock Characteristics, Predictors and Clinical Outcomes

Jun 9, 2026

The authors aimed to investigate the incidence, predictors, and clinical outcomes of refractory versus recurrent ventricular fibrillation (VF) in patients experiencing out-of-hospital cardiac arrest (OHCA). They found that only 5% of patients had refractory VF, which was associated with poorer resuscitation characteristics and uncertain clinical outcomes compared to those with recurrent VF. Key predictors for refractory VF included the absence of CPR and AED use prior to EMS arrival, longer delays to the first shock, and lower amplitude spectral area values.