A randomised controlled trial of defibrillation with manual pressure augmentation during out-of-hospital cardiac arrest
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The authors aimed to determine whether defibrillation with manual pressure augmentation (MPA) could reduce transthoracic impedance and improve survival rates in patients experiencing out-of-hospital cardiac arrest (OHCA) with a shockable rhythm, compared to standard defibrillation. The study found that while MPA significantly reduced transthoracic impedance, it did not lead to improved survival or other clinical outcomes. The trial was prematurely terminated, and compliance with the MPA intervention was low.
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