May 2, 2026 · Resuscitation · DOI: 10.1016/j.resuscitation.2026.111115

A systematic review of mortality and severe morbidities following newborn chest compressions at birth

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The authors aimed to synthesize evidence regarding mortality and severe morbidities following delivery room chest compressions (CC) in newborns, examining variations by birth setting, gestation, and level of care. They found significant variability in mortality rates (21-74%) and severe neurological injury (16-42%) among different infant groups, highlighting a lack of consistent definitions and reporting standards across studies. The review emphasizes the need for prospective research to better understand outcomes and improve neonatal resuscitation practices.

Wubet Alebachew Bayih, Kathryn Eastwood, Helen Liley, Jacinta Trang, Julena Ardern, Kylie Choong, Janet Bray

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