May 9, 2026 · The American journal of emergency medicine · DOI: 10.1016/j.ajem.2026.04.035

Etiology-specific predictors for short-term functional outcomes of OHCA: A Japanese Nationwide registry study

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This study aimed to identify etiology-specific predictors of favorable functional outcomes after out-of-hospital cardiac arrest (OHCA) using data from a nationwide Japanese registry. The results indicated that early defibrillation was a strong predictor of favorable outcomes in cardiac-origin OHCA, while cerebrovascular-origin OHCA outcomes appeared to be more influenced by the initial severity of cerebral injury rather than resuscitation timing. The authors suggest that further prospective studies are needed to validate these findings due to the limitations of their registry-based research.

Satoru Hanada, Michikazu Nakai, Shohei Koyama, Hironao Iwakiri, Koichi Kaikita, Naohiro Yonemoto, Tetsuya Matoba, Yoshio Tahara, Japanese Circulation Society with Resuscitation Science Study (JCS-ReSS) Investigators

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