June 9, 2026 · Resuscitation · DOI: 10.1016/j.resuscitation.2026.111167

Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study

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The authors aimed to investigate the characteristics, treatment patterns, and outcomes of patients experiencing cardiac arrest due to pulmonary embolism (PE) using a nationwide inpatient database in Japan from 2012 to 2024. They found that while the use of thrombolytic therapy decreased, the use of extracorporeal membrane oxygenation (ECMO) increased, leading to improved survival rates and favorable neurological outcomes over time, particularly among patients with hospital-acquired PE. Overall, the study highlights significant trends in treatment and outcomes for this high-mortality condition.

Keiichi Ishida, Yuji Nishimoto, Hiroyuki Ohbe, Yugo Yamashita, Makoto Mo, Yuya Kimura, Hiroki Matsui, Hideo Yasunaga

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