June 9, 2026 · Resuscitation · DOI: 10.1016/j.resuscitation.2026.111163

Prognostic Performance of Plasma and Urinary Biomarkers of Kidney Injury and Function After Out-Of-Hospital Cardiac Arrest

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The authors aimed to determine whether kidney injury biomarkers could enhance the early prediction of patient-centered outcomes and acute kidney injury (AKI) following out-of-hospital cardiac arrest (OHCA), compared to serum creatinine (sCr). Their findings indicate that plasma and urinary biomarkers, particularly urinary NGAL, significantly outperformed sCr in predicting poor neurological recovery and AKI, suggesting that these biomarkers could improve risk stratification in clinical settings.

Shir Lynn Lim, Kai Lee Woo, Amy Ym Au, Marcus Eh Ong, Arthur Mark Richards, Zoltan H Endre, John W Pickering

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