June 10, 2026 · Journal of the American College of Cardiology · DOI: 10.1016/j.jacc.2026.03.056

2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

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The 2026 AHA/ACC/ADA/ASN Guideline aims to enhance the prevention, detection, evaluation, and management of cardiovascular-kidney-metabolic syndrome, which encompasses the interrelated conditions of metabolic risk factors, chronic kidney disease, and cardiovascular disease. This guideline replaces the 2013 version and is designed for clinicians treating patients with these interconnected health issues, providing updated evidence and recommendations based on a comprehensive literature review. The authors seek to create a dynamic resource that reflects the latest knowledge in managing this complex syndrome.

Chiadi E Ndumele, Fatima Rodriguez, Dave L Dixon, Sadiya S Khan, Debabrata Mukherjee, Mandeep Bajaj, Sripal Bangalore, Biykem Bozkurt, Khadijah Breathett, Shoa L Clarke, Ian H de Boer, David H Ellison, Lorraine S Evangelista, Sean P Heffron, Dhruv S Kazi, Ambar Kulshreshtha, Ildiko Lingvay, Cecilia C Low Wang, Claudia A Mercado, John Magaña Morton, Ian J Neeland, Neha Pagidipati, Tiffany M Powell-Wiley, Janani Rangaswami, Goutham Rao, Nosheen Reza, Anum Saeed, Wendy St Peter, J Bradley Starks, Madeline Sterling, Amy W Talbot, Andrew H Tran, Katherine R Tuttle, Lisa B VanWagner, Amanda R Vest, Salim S Virani

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