June 10, 2026 · Journal of the American College of Cardiology · DOI: 10.1016/j.jacc.2026.04.037

Angiographic Quantitative Flow Ratio-Guided Coronary Intervention: 5-Year Follow-Up From the FAVOR III China Randomized Trial

Listen to this summary

The study aimed to assess the long-term effectiveness and safety of quantitative flow ratio (QFR)-guided percutaneous coronary intervention (PCI) compared to angiography-guided PCI over a 5-year period. Results indicated that QFR guidance significantly reduced major adverse cardiac events, particularly myocardial infarctions and ischemia-driven revascularizations, with most benefits occurring within the first two years. However, all-cause mortality rates were similar between the two groups, suggesting that while QFR guidance improves outcomes, its advantages may diminish over time.

Han Zhang, Changdong Guan, Zening Jin, Bo Yu, Guosheng Fu, Yujie Zhou, Jian'an Wang, Yundai Chen, Jun Pu, Lianglong Chen, Xinkai Qu, Junqing Yang, Xuebo Liu, Lijun Guo, Chengxing Shen, Yaojun Zhang, Qi Zhang, Hongwei Pan, Jian Liu, Yanyan Zhao, Yang Wang, Kefei Dou, Ajay J Kirtane, Yongjian Wu, Weixian Yang, Shubin Qiao, Shengxian Tu, Gregg W Stone, Lei Song, FAVOR III China Study Group

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play