June 7, 2026 · Journal of cutaneous pathology · DOI: 10.1111/cup.70148

Dermatofibroma Hypocellularity Is Associated With Patient Age: A Retrospective Study of 307 Cases

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This study investigates the relationship between patient age and the prevalence of hypocellular dermatofibromas, a variant of benign fibrohistiocytic neoplasms. The authors found a significant positive correlation, indicating that the frequency of hypocellular dermatofibromas increases with age, suggesting that these lesions may undergo gradual involution and reduced cellular density over time.

Christian Jordan, Wesley Hodges, Laura Russell, Albert Alhatem, Eric Armbrecht, Gillian Heinecke, Kristin Smith, Nicole Burkemper, M Yadira Hurley

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