DREAM Promotes Intestinal Adaptation and Restores Enterohepatic Signaling in Short Bowel Syndrome

The authors investigate the efficacy of DREAM (Distal Recirculation of Enteral contents Augmented Mechanically) in promoting intestinal adaptation and restoring enterohepatic signaling in short bowel syndrome (SBS), a condition that leads to malabsorption and liver disease. Their findings demonstrate that DREAM significantly improves growth, intestinal morphology, and gut-liver homeostasis while preventing intestinal and hepatic injury associated with SBS, suggesting it as a promising therapeutic approach for enhancing enteral nutrition in affected patients.