June 9, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.05.038

Sleep Apnea and the Ageing Brain: Bridging Mechanisms and Clinical Outcomes

Listen to this summary

This paper investigates the relationship between obstructive sleep apnea (OSA) and cognitive decline in aging individuals, exploring the underlying mechanisms that may contribute to this association. The authors highlight the multifactorial pathophysiology of OSA, including intermittent hypoxia and neuroinflammation, while noting the uncertainty surrounding the cognitive benefits of OSA treatment, particularly continuous positive airway pressure (CPAP). They call for further research to clarify the impact of OSA treatment on cognitive outcomes and to identify effective intervention strategies.

Anastasya Maria Kosasih, Yao Feng Chong, Pei-Lin Lee, Juan Helen Zhou, Diane C Lim, Chi-Hang Lee

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play