Optimal Medical Therapy in Patients with Chronic Coronary Syndrome Undergoing PCI: Temporal Trends and Outcomes

The authors aimed to evaluate temporal trends in optimal medical therapy (OMT) among patients with chronic coronary syndrome undergoing percutaneous coronary intervention (PCI) and its impact on outcomes, particularly major adverse cardiovascular events (MACE). They found that while there was an increase in the proportion of patients receiving more intensive therapy and improved risk factor control, those on high-intensity therapy experienced higher rates of MACE compared to those on low-intensity therapy, indicating that residual risk persists despite advancements in treatment.