June 5, 2026 · European heart journal · DOI: 10.1093/eurheartj/ehag404

Extracellular vesicles in atherosclerotic cardiovascular disease: mechanisms and therapeutic implications

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The authors investigate the role of extracellular vesicles (EVs) in the mechanisms underlying atherosclerotic cardiovascular disease and their potential as therapeutic targets. They highlight how EVs from various cell types contribute to inflammation, plaque formation, and instability in atherosclerosis, suggesting that manipulating EVs could provide new strategies for monitoring and treating this condition. The study emphasizes the need for further exploration of EVs as biomarkers and therapeutic agents in atherosclerosis management.

Nicolas Amabile, Elena Aikawa, Françoise Dignat-George, Chantal M Boulanger, Yao Yao, Aurélie S Leroyer

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