June 4, 2026 · Radiographics : a review publication of the Radiological Society of North America, Inc · DOI: 10.1148/rg.250098

WHO 2022 Renal Cell Tumor Classification: Imaging Features and Clinical Implications

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The authors aim to elucidate the implications of the WHO's 2022 classification of renal cell tumors, which introduces significant changes by categorizing epithelial renal tumors into six groups, including major subtypes and newly defined molecularly characterized tumors. They emphasize the importance of recognizing distinct imaging features that can help differentiate these rare subtypes from typical papillary renal cell carcinoma, thereby aiding in surgical planning and accurate diagnosis. The study highlights the evolving landscape of renal tumor classification and the need for careful evaluation of imaging characteristics to inform clinical decision-making.

Masahiro Jinzaki, Refky Nicola, Samuel J Withey, Jurgen J Fütterer, Hirotaka Akita, Akira Yamamoto, Orito Ikeda, Fumiko Yagi, Toyonori Tsuzuki, Holger Moch

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