Radiographics : a review publication of the Radiological Society of North America, Inc
Audio Summaries

Opportunistic CT Screening: Clinical Applications, Technical Foundations, and Best Practices

Sep 17, 2026

The authors explore the potential of opportunistic CT screening to identify clinically relevant biomarkers from routine CT scans conducted for unrelated reasons, aiming to address the challenges of integrating this practice into clinical workflows. They discuss the advancements in automated image analysis and AI, the importance of these biomarkers in assessing various health risks, and the barriers to widespread adoption, including issues of standardization and the risk of overdiagnosis. Ultimately, the review seeks to guide healthcare professionals in effectively implementing opportunistic CT screening in clinical settings.

Pancreatic Cancer Screening and Early Detection: Where Are We Now?

Sep 17, 2026

The authors examine the current state of pancreatic cancer screening and early detection, particularly for high-risk individuals, in light of the disease's poor prognosis due to late-stage diagnosis. They aim to evaluate existing screening strategies, emerging imaging technologies, and novel serum biomarkers that could enhance early detection and improve clinical outcomes. The paper highlights the need for validated, cost-effective tools to address the challenges in early diagnosis of pancreatic cancer.

Targeted US Screening in High-Risk Newborns and Infants: Indications, Techniques, and Disease Findings

Sep 10, 2026

The authors aim to outline effective ultrasound (US) screening strategies for high-risk newborns and infants who are at increased risk for significant diseases due to perinatal exposures, congenital conditions, and genetic syndromes. They discuss the rationale for targeted screening, optimal timing, technical considerations, and key imaging findings that inform management decisions, emphasizing the importance of risk-based selection and standardized protocols. Ultimately, the paper highlights how structured screening can facilitate early diagnosis and improve outcomes in vulnerable pediatric populations.

Breast Cancer Screening in Pregnant and Lactating Patients: A Practical Approach

Sep 10, 2026

The authors aim to address the challenges and considerations surrounding breast cancer screening in pregnant and lactating patients, particularly in light of increased incidence and the impact of physiological changes on imaging results. They review current guidelines and the effectiveness of various imaging modalities, such as mammography, ultrasound, and MRI, while emphasizing the importance of balancing diagnostic accuracy with maternal and fetal safety. The paper also discusses strategies for identifying high-risk patients and effectively communicating the risks and benefits of screening to both patients and healthcare providers.

Surveillance for Hepatocellular Carcinoma in Patients at High Risk

Sep 3, 2026

The authors investigate effective surveillance strategies for hepatocellular carcinoma (HCC) in high-risk patients, emphasizing the limitations of current standard practices, such as semiannual ultrasound and serum α-fetoprotein testing. They explore alternative approaches, including biomarker panels and abbreviated MRI protocols, which may offer improved sensitivity and cost-effectiveness for specific patient subgroups. Additionally, the paper addresses the barriers to optimal surveillance implementation in clinical settings and advocates for personalized, risk-adapted surveillance strategies.

Lung Cancer Screening: Beyond Pulmonary Nodules

Sep 3, 2026

The authors investigate how low-dose CT lung cancer screening can be optimized to identify incidental findings beyond lung cancer, which may significantly impact patient management and outcomes. They propose a practical framework for recognizing, reporting, and managing these findings, emphasizing the importance of standardized assessment methods and the integration of artificial intelligence tools to enhance opportunistic screening. The study aims to demonstrate that lung cancer screening can serve as a valuable tool for comprehensive risk stratification and preventive care, addressing the challenges posed by incidental findings.

Navigating PI-RADS 3 Lesions: Reducing Uncertainty and Guiding Prostate Cancer Diagnostic Decision Making

Aug 27, 2026

The authors aim to address the diagnostic challenges associated with PI-RADS 3 lesions, which have an ambiguous likelihood of clinically significant prostate cancer, leading to potential overdiagnosis and overtreatment. They discuss factors contributing to the prevalence of these lesions and propose strategies, such as structured reporting and the integration of ancillary biomarkers, to enhance diagnostic accuracy and guide clinical decision-making. By understanding the limitations and evolving management strategies for PI-RADS 3 lesions, the authors seek to improve patient outcomes and reduce unnecessary interventions.

MRI of Hepatocellular Carcinoma: Cross-regional Perspectives on Trends and Opportunities

Aug 27, 2026

The authors investigate the regional differences in the use of MRI for the management of hepatocellular carcinoma (HCC), focusing on how these variations impact surveillance, diagnosis, and treatment monitoring across Eastern and Western healthcare systems. They highlight how differences in disease prevalence, treatment practices, and reimbursement policies influence MRI guidelines and diagnostic criteria for HCC. The paper emphasizes the importance of recognizing these regional variations for the interpretation of international studies and enhancing global collaboration in HCC management.

US Tissue Harmonic and Spatial Compound Imaging: What Are They and How Do They Change the Image?

Aug 27, 2026

The authors aim to clarify the concepts of tissue harmonic and spatial compound imaging in ultrasound (US) and their impact on image quality. They explore how these advanced imaging techniques, which have been in clinical use for over two decades, can enhance image clarity by reducing noise and artifacts, both individually and in combination. The paper addresses the ongoing uncertainty in the understanding and application of these imaging methods in clinical practice.

Presacral Masses: Comprehensive Guide with Radiologic-Pathologic Correlation

Aug 20, 2026

The authors aim to provide a comprehensive guide on presacral masses, focusing on their characterization through imaging techniques and the importance of radiologic-pathologic correlation. They discuss the prevalence of malignant lesions, the role of MRI in diagnosis and preoperative planning, and criteria for distinguishing between benign and malignant lesions. Additionally, the paper outlines management strategies, including surveillance and surgical options, based on imaging findings.