June 11, 2026 · Radiographics : a review publication of the Radiological Society of North America, Inc · DOI: 10.1148/rg.250192

Factors Affecting Contrast Enhancement on CT Images

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The authors investigate the various factors that influence contrast enhancement in CT images, aiming to optimize the administration of iodinated contrast media (ICM) for improved diagnostic utility. They categorize these factors into physics-based, patient-related, and contrast protocol-based elements, further stratifying them into scalar, temporal, and sampling factors. Understanding these interactions is essential for enhancing image quality and minimizing the need for repeat examinations.

Zahra Alyani Nezhad, Giuseppe V Toia, Sean D Rose, Rachel M Bladorn, Timothy P Szczykutowicz

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