May 12, 2026 · Journal of addictive diseases · DOI: 10.1080/10550887.2026.2667987

Cannabis Use Disorder as a disorder of motivational dysregulation: a systematic review of clinical, neurocognitive, and treatment evidence

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This systematic review investigates whether Cannabis Use Disorder (CUD) can be reconceptualized as a disorder of motivational dysregulation by examining clinical, neurocognitive, and treatment evidence from the past decade. The findings suggest that motivational factors, such as ambivalence and diminished goal pursuit, play a critical role in CUD, and interventions targeting motivation yield better treatment outcomes than traditional abstinence-focused approaches. Ultimately, the authors advocate for a shift in understanding CUD to enhance assessment and treatment strategies.

Sidharth Mishra, Sayali Mishra, Ashwini Rajmohan, Sibanarayan Rath

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