May 1, 2026 · Journal of addictive diseases · DOI: 10.1080/10550887.2026.2639428

Underutilization of PETH testing among patients with MASLD - retrospective, single-center evaluation of the frequency and results of phosphatidylethanol testing among patients diagnosed with metabolic dysfunction-associated liver disease

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This study aimed to evaluate the frequency and results of phosphatidylethanol (PETH) testing among patients diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD). The authors found that PETH testing was underutilized, conducted in only 6.9% of patients, yet nearly 40% of those tested had positive results, suggesting that PETH testing could play a crucial role in managing MASLD by identifying potentially harmful alcohol use. However, the study also indicated that existing patient and laboratory characteristics were inadequate for predicting positive PETH results.

Annabel McLaughlin, Margot Manning, Michelle Lai, Zachary P Fricker

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