May 7, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.04.025

Prognostic Utility of Serum Beta Human Chorionic Gonadotropin Level following Single Euploid Embryo Transfer for Live Birth

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The authors aimed to determine the prognostic value of initial serum human chorionic gonadotropin (hCG) levels following single euploid embryo transfer in predicting live birth outcomes. Their retrospective cohort study found a significant stepwise increase in live birth rates correlating with higher hCG levels, with the optimal threshold identified at approximately 75.7 mIU/mL. These results highlight the importance of initial hCG measurements as a counseling tool for patients undergoing this fertility treatment.

Emily A Clarke, Charlotte Jones, Jensen Reckhow, Kerry Flannagan, Diana Shaari, Morgan Baird, Joseph A Lee, Lucky Sekhon, Alan B Copperman, Phillip A Romanski

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