May 6, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.03.032

Intracytoplasmic sperm injection for nonmale factor indications: a Committee opinion

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This committee opinion evaluates the use of intracytoplasmic sperm injection (ICSI) in cases of infertility that do not involve male factor issues, despite normal semen parameters. The authors aim to identify specific scenarios where ICSI may be beneficial or not, based on a critical review of the existing literature. This document updates previous guidelines published in 2020.

Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology

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