April 26, 2026 · American journal of obstetrics and gynecology · DOI: 10.1016/j.ajog.2026.04.027

EVALUATION OF WEIGHT CHANGE DURING OVARIAN STIMULATION TREATMENT

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The authors aimed to determine the mean weight change experienced by patients undergoing ovarian stimulation treatment and to assess variations in weight change among those diagnosed with ovarian hyperstimulation syndrome and those undergoing multiple cycles. Their retrospective study of over 22,000 stimulation cycles found an average weight gain of 0.64 kg, with higher gains associated with lower initial body mass index and greater oocyte retrieval, although differences related to ovarian hyperstimulation syndrome were not statistically significant. Overall, the study highlights that weight changes during ovarian stimulation are generally modest and temporary.

Simone Elder, Kerry Flannagan, Phillip Romanski, Laura Zalles, Cassandra Roeca

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