Cytotoxic lesion of the corpus callosum after gamma hydroxybutyrate withdrawal: a case report

This case report investigates the neuroimaging correlates of neurotoxicity associated with withdrawal from gamma-hydroxybutyrate (GHB), particularly focusing on the occurrence of cytotoxic lesions in the corpus callosum. The authors present a case of a 33-year-old male who experienced severe withdrawal symptoms and a focal splenial lesion, suggesting that such lesions may serve as significant indicators of GHB withdrawal-related neurotoxicity. The findings highlight the need for further research into the neurological effects of GHB withdrawal.