April 9, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2025-089001

Non-drug perioperative interventions to reduce postoperative pulmonary complications after abdominal surgery: systematic review and meta-analysis

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The authors aimed to evaluate the effectiveness of non-drug perioperative interventions in reducing postoperative pulmonary complications (PPCs) in adults undergoing abdominal surgery. Their systematic review and meta-analysis of 255 trials involving over 55,000 participants found that low fraction of inspired oxygen (FiO2) significantly reduced PPCs, while other interventions such as lung protective ventilation, physiotherapy, analgesia, and nutrition also showed moderate benefits. The study highlights the importance of prioritizing these effective strategies in clinical practice to enhance patient outcomes.

Chanyan Huang, Xu Zhao, Siyu Geng, Shujun Sun, Nada M Mousa, Haohan Xia, Xuanxian Xu, Jie Deng, Xiaolin Lu, Dan Xu, Bingcheng Zhao, Matthew Lim, Yi Li, William Tang, Xinran Chen, Fang Gao Smith, Ce Tang, Xia Feng

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