March 13, 2026 · Journal of the American College of Radiology : JACR · DOI: 10.1016/j.jacr.2026.02.012

ACR Appropriateness Criteria® Staging and Follow-Up of Pancreatic Neuroendocrine Tumors

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The authors aim to provide evidence-based recommendations for the imaging evaluation of pancreatic neuroendocrine tumors (PNET) across various clinical scenarios, including staging and follow-up. They emphasize the use of contrast-enhanced CT as the primary imaging modality, with MRI and DOTATATE PET/CT serving important roles in specific cases, particularly for liver evaluation and metastatic disease. The guidelines are informed by a systematic review of the literature and expert consensus to ensure appropriate imaging practices for optimizing patient management.

Expert Panel on Gastrointestinal Imaging, Joseph H Yacoub, Motoyo Yano, Kevin J Chang, Emily Bergsland, Priya R Bhosale, Brooks D Cash, Victoria Chernyak, Ayushi Gupta, Julie Hallet, Jason Halpern, Michael Magnetta, Craig F Noronha, Tamer Refaat, Elena K Korngold

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