Cowden Syndrome: Imaging Review and Cancer Surveillance

This article reviews Cowden syndrome (CS), a genetic disorder linked to mutations in the PTEN gene, which predisposes individuals to various malignancies and hamartomatous lesions. The authors aim to outline the clinical manifestations, imaging features, and updated cancer surveillance recommendations for early diagnosis and management of patients with CS. They emphasize the importance of comprehensive evaluation and specific imaging strategies to monitor the increased cancer risk associated with this syndrome.