March 7, 2026 · Journal of hepatology · DOI: 10.1016/j.jhep.2026.02.027

BCLC classification and AI-based image quantification: What is meant to be will come together - but how and when?: BCLC and AI-based image quantification

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The authors investigate how artificial intelligence (AI) can enhance the existing Barcelona Clinic Liver Cancer (BCLC) classification for hepatocellular carcinoma (HCC) by integrating advanced imaging quantification techniques. They aim to identify the potential synergies between AI-based imaging parameters and the BCLC classification, while addressing the challenges that hinder the clinical implementation of AI in routine care.

Lukas Müller, Jakob N Kather, Jens U Marquardt, Maria Reig, Qiang Wang, Daniel Pinto Dos Santos, Roman Kloeckner

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