March 20, 2026 · BMJ (Clinical research ed.) · DOI: 10.1136/bmj-2025-085810

Effect of a clinical decision support system on stroke care quality and outcomes in patients with acute ischaemic stroke (GOLDEN BRIDGE II): cluster randomised clinical trial

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The authors aimed to evaluate the effectiveness of a clinical decision support system (CDSS) on the quality of stroke care and clinical outcomes in patients with acute ischaemic stroke. The study, conducted across 77 hospitals in China, found that the CDSS significantly reduced new vascular events at three months and improved care quality compared to usual care, without increasing the risk of bleeding or affecting disability and mortality rates.

Xinmiao Zhang, Lingling Ding, Jing Jing, Chunjuan Wang, Hongqiu Gu, Yong Jiang, Xia Meng, Tao Liu, Xuewei Xie, Man Xu, Meera Hu, Yanxu Zhang, He Fu, Pan Liu, Chunying Du, Kejin Du, Meng Wang, Hao Li, Xiping Gong, Kehui Dong, Yunyun Xiong, Yilong Wang, Liping Liu, Zaihui Zhang, Yingzhuo Zang, Chunxiang Yang, Ying Xian, Eric Peterson, Gregg C Fonarow, Lee H Schwamm, Xingquan Zhao, Yongjun Wang, Zixiao Li, GOLDEN BRIDGE II Investigators

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