Menopause
Audio Summaries

Characterizing the role of menopausal status and hormone therapy on modifiable health behaviors and their association with body composition, physical function, and metabolic health

Jun 22, 2026

This study aimed to characterize how menopausal status and hormone therapy (HT) influence the relationships between modifiable health behaviors (MHBs) and various health outcomes over time. Analyzing data from the Canadian Longitudinal Study on Aging, the authors found that physical activity and sleep had evolving associations with body composition and physical function, particularly in postmenopausal women, highlighting the need to consider these factors in aging-related health assessments.

Menopausal symptoms in average-age menopause and premature ovarian insufficiency

Jun 22, 2026

This study investigates the prevalence and severity of menopausal symptoms among Canadian women experiencing menopause at the average age compared to those with premature ovarian insufficiency. The findings reveal that both groups report common and often severe symptoms, particularly urogenital issues, with women undergoing average-age menopause experiencing a greater overall symptom burden. The results highlight the importance of comprehensive symptom assessment and management for all individuals facing estrogen deficiency, regardless of age.

Nocturia in postmenopausal women

Jun 22, 2026

This article investigates the prevalence and contributing factors of nocturia in postmenopausal women, a condition that significantly impacts their quality of life. The authors aim to understand the etiology of nocturia, considering hormonal, anatomical, functional, and psychosocial changes during the postmenopausal period, in order to inform targeted treatment strategies.

Physical activity and health-related quality of life in Korean postmenopausal women with and without chronic diseases: a population-based study using the KNHANES 2016-2020 database

Jun 16, 2026

The authors aimed to investigate the relationship between physical activity (PA) and health-related quality of life (HRQoL) in Korean postmenopausal women, particularly considering the impact of chronic diseases. Their findings indicate that higher levels of PA, especially light-to-moderate activities like walking, are associated with improved HRQoL, with more pronounced benefits observed in women with chronic conditions. This underscores the importance of promoting appropriate PA and reducing sedentary behavior to enhance well-being in this population.

Impact of menopause on subfoveal choroidal thickness: population-based evidence from the 2017 to 2021 KNHANES

Jun 16, 2026

The authors aimed to investigate the relationship between menopausal status, oral contraceptive use, and subfoveal choroidal thickness in a nationally representative sample of Korean women. Their findings indicate that neither menopausal status nor oral contraceptive use significantly affected choroidal thickness or central macular thickness, although an interaction with blood pressure suggests that the effects may vary among different cardiovascular risk groups, warranting further study.

The association between cardiorespiratory fitness, cardiovascular disease risk factors, and quality of life in perimenopausal and postmenopausal women: a cross-sectional study

Jun 16, 2026

This study aimed to investigate the relationships between cardiorespiratory fitness (CRF), cardiovascular health markers, and quality of life in perimenopausal and postmenopausal women. The findings indicate that higher CRF is associated with a more favorable cardiometabolic risk profile and fewer menopause-related symptoms, although no significant links were found between CRF and vascular function. This suggests that while CRF may benefit cardiovascular health and quality of life during menopause, other factors may influence vascular health more significantly.

A novel negative pressure treatment for the genitourinary syndrome of menopause: a feasibility pilot study with the VITA AV clinical system

Jun 16, 2026

The authors aimed to assess the feasibility, effectiveness, and safety of a novel negative pressure device, the VITA AV Clinical System, for treating genitourinary syndrome of menopause (GSM) in women. The pilot study found that the treatment was well-tolerated, with many participants reporting symptom improvement and no adverse events. The results indicate potential benefits, warranting further controlled studies with larger sample sizes to evaluate long-term effects.

Menopause and hormone therapy in relation to dietary intake, physical activity, and sleep, and meeting lifestyle guidelines

Jun 16, 2026

This study investigates how menopause and hormone therapy (HT) influence modifiable health behaviors (MHBs) such as dietary intake, physical activity, and sleep among women. The analysis of data from over 10,000 participants reveals that postmenopausal women, particularly those who have never used HT, report lower fruit and vegetable intake, reduced likelihood of meeting strength-based activity guidelines, and shorter sleep duration compared to pre/perimenopausal women. The findings emphasize the importance of considering hormonal and life-stage factors in promoting healthy aging among females.

Therapeutic strategies for postmenopausal atherosclerosis: a systematic review of drug interventions in animal models

Jun 16, 2026

This systematic review investigates the efficacy of various therapeutic interventions for postmenopausal atherosclerosis using animal models, particularly those involving ovariectomy to simulate estrogen deficiency. The authors found that estrogen-based therapies were the most extensively studied and generally improved lipid profiles and inflammatory markers, although the effectiveness varied across different models and treatment protocols. The study emphasizes the need for standardized research designs and further translation into human trials to enhance the prevention and treatment of cardiovascular disease in postmenopausal women.

FDA safety concerns and menopausal-like symptoms in postmenopausal statin users

Jun 16, 2026

The authors aimed to investigate the relationship between statin therapy and menopausal-like symptoms in postmenopausal women, particularly in light of FDA warnings regarding statin side effects. The study found that statin users experienced significantly more severe menopausal symptoms, musculoskeletal issues, and higher sarcopenia risk compared to non-users, although statin use was not associated with mild cognitive impairment. These findings suggest that the cognitive and physical effects of statins may overlap with menopausal symptoms, potentially increasing the symptom burden for women in midlife.