March 15, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.03.011

Varicocele and Low Testosterone

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The authors investigate the relationship between varicocele and testosterone levels, particularly how varicocele repair may influence testosterone production in men with low testosterone. They highlight that patients undergoing varicocelectomy can experience significant increases in testosterone levels, suggesting that this surgical intervention, alongside lifestyle changes, may alleviate testosterone deficiency without the need for medication. The review calls for further research to identify predictors of testosterone improvement post-surgery and to assess the clinical significance of these changes.

Grant L Steele, Cigdem Tanrikut

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