March 19, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.03.020

Intra-Patient Variability in the Number of Retrieved Oocytes and Ovarian Response Categories Between Consecutive IVF Cycles

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The authors aimed to investigate the intra-patient variability in the number of retrieved oocytes across consecutive IVF cycles using the same ovarian stimulation protocol. Their findings revealed significant fluctuations in oocyte yield, with nearly half of the patients experiencing shifts in ovarian response categories, highlighting the challenges in predicting ovarian response based solely on previous cycle outcomes. This variability underscores the need for improved performance indicators in IVF treatment protocols.

Alyssa Hochberg, Shachar Reuvenny, Nevo Itzhak, Almog Luz, Rohi Hourvitz, Eden Moran, Nikolaos P Polyzos, Eduardo Hariton, Wenjing Zheng, Thomas D'Hooghe, Ettie Maman, Micha Baum, Michal Youngster, Ariel Hourvitz

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