Lymphatic mapping and sentinel node biopsy in invasive Vulvar Paget's disease: A retrospective study and systematic review of the literature
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This study aimed to evaluate the oncologic outcomes of sentinel node biopsy (SNB) in patients with invasive Vulvar Paget's Disease (iVPD). The findings indicate that SNB is a feasible and effective method for nodal staging in iVPD, with a notable rate of metastatic sentinel nodes in patients with microinvasive disease, suggesting the need for inguino-femoral surgical staging in this population. Overall, the study supports the expansion of SNB indications for vulvar neoplasms.
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