March 2, 2026 · Gynecologic oncology reports · DOI: 10.1016/j.gore.2026.102049

Is pregnancy feasible in women with adult granulosa cell tumors, and how should recurrence during pregnancy be managed? A case report and literature review

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The authors investigate the feasibility of pregnancy in women with adult granulosa cell tumors (aGCT) and the management of disease recurrence during gestation, highlighting the need for individualized treatment strategies. They present a case of a woman diagnosed with FIGO IC aGCT who experienced recurrences during pregnancy, successfully managed through surgical intervention while maintaining the health of both mother and child. This case underscores the complexities involved in treating aGCT during pregnancy and the necessity of a multidisciplinary approach for optimal outcomes.

Moritz Matthaei, B Gebauer, A Kunze, W Schmitt, D Dimitrova, J Sehouli

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