Age-Associated Cognitive Deviations in Early-Onset Psychosis Patients and Their Siblings

This study aimed to investigate cognitive impairments and age-associated cognitive deviations in children and adolescents with early-onset psychosis (EOP), their siblings, and nonpsychotic psychiatric controls. The findings revealed that nonaffective EOP probands exhibited impairments across all cognitive measures, while affective EOP probands showed impairments in most areas, with siblings demonstrating no impairments. The results suggest that targeted early interventions may help mitigate cognitive deviations, although longitudinal studies are necessary to validate these cross-sectional findings.