Prognostic Value of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve From a Large Nationwide Cohort

The authors aimed to investigate the prognostic value of coronary computed tomography angiography-derived fractional flow reserve (FFR-CT) in predicting future cardiovascular events in a large nationwide cohort over a three-year follow-up period. They found that lower FFR-CT values were significantly associated with increased risks of myocardial infarction, cardiovascular mortality, and all-cause mortality, with a threshold of 0.67 identified as optimal for predicting these outcomes. The study highlights the importance of FFR-CT measurements in assessing cardiovascular risk beyond traditional factors and stenosis severity.