September 21, 2026 · Circulation · DOI: 10.1161/CIRCULATIONAHA.126.080727

Acute Coronary Syndrome in Kawasaki Disease From Infancy to Adulthood

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The authors aim to address the underrecognition of acute coronary syndrome (ACS) in patients with Kawasaki disease (KD) and highlight the need for tailored management strategies that differ from traditional atherosclerotic disease guidelines. They review current evidence on the unique epidemiology, pathophysiology, and treatment approaches for KD-associated ACS, emphasizing the importance of collaboration between pediatric and adult cardiologists to improve clinical outcomes.

Pei-Ni Jone, Jane W Newburger, Jane C Burns, Matthew I Tomey, André Jakob, Yasutsugu Shiono, Satsuki Fukushima, Yoshihide Mitani, Ming-Tai Lin, Alain Fraisse, Hirosyohi Yokoi, Tosihiro Tamura, Nadine Choueiter, Jiken Bhatt, Luis G Quinonez, Etsuko Tsuda, Nagib Dahdah, John B Gordon, Kenji Suda

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