Reliability and Validity of Imaging-derived Extranodal Extension Grading Using CT and MRI in Nasopharyngeal Carcinoma
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The authors aimed to evaluate the reliability and prognostic value of a proposed imaging-derived extranodal extension (iENE) grading system in patients with nasopharyngeal carcinoma (NPC). The study found that the iENE grading demonstrated excellent inter- and intrarater reliability and was associated with significant differences in overall survival and distant metastasis-free survival, indicating its potential as a valuable prognostic tool in NPC staging.
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