September 21, 2026 · Journal of pediatric orthopedics · DOI: 10.1097/BPO.0000000000003467

Spinal Fusion in Prader-Willi Syndrome: Early Radiographic Outcomes and Complications With a Subset Analysis of Two-year Follow-up in a Multicenter Cohort

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The authors aimed to evaluate the early radiographic outcomes and complications associated with spinal fusion in patients with Prader-Willi syndrome (PWS), a population known for a high incidence of scoliosis and surgical challenges. Their findings indicate that while spinal fusion leads to significant and durable correction of spinal deformities, it is also associated with a notable risk of perioperative complications and unplanned return to the operating room, particularly in patients with higher body mass index. This underscores the necessity for tailored risk assessment and perioperative management in this vulnerable group.

Amanda G Lobato, Lindsay Andras, Majella Vaughan, Brandon A Ramo, Jessica L McQuerry, Aaron J Huser, David S Feldman, Arun R Hariharan, Pediatric Spine Study Group

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