A Novel Mini-Prosthesis with a Nano-Multilayer Film-Coated Surface and 3D-Printed Porous Stem for Focal Cartilage Lesions: In Vivo Performance in a Porcine Model
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This study investigates the in vivo performance of a novel mini-prosthesis designed for treating focal cartilage lesions (FCLs) in a porcine model, comparing it to existing options. The results indicate that the Ti6Al4V mini-prosthesis with a nano-multilayer film-coated surface and a 3D-printed porous stem (NMF@3D-Ti) demonstrated superior biocompatibility, osseointegration, and cartilage protection compared to traditional prostheses and microfracture techniques. These findings suggest that the NMF@3D-Ti mini-prosthesis could be a promising joint-preserving alternative in the management of osteoarthritis.
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