Platelet Concentration Is Not Associated With Improved Pain for Partial-Thickness Rotator Cuff Tears Treated With Platelet-Rich Plasma: A Systematic Review and Meta-analysis With Meta-regression of Level 1 Randomized Controlled Trials

The authors aimed to determine whether the concentration of platelets in platelet-rich plasma (PRP) injections influences pain relief, as measured by visual analog scale (VAS) scores, in patients with partial-thickness rotator cuff tears. Their systematic review and meta-analysis of level 1 randomized controlled trials found no significant differences in pain outcomes between high-dose and low-dose PRP groups. The authors noted that variability in study methodologies and PRP composition may affect the reliability of these findings.