Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9-23 months in Uganda: a phase 4, single-blind, randomised clinical trial
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This study aimed to evaluate the immunogenicity of fractional doses (one-fifth and one-half) of the 17DD yellow fever vaccine compared to the full dose in children aged 9-23 months in Uganda. The findings demonstrated that both fractional doses were non-inferior to the full dose in terms of seroconversion, suggesting their potential use for vaccination during supply shortages in young children.
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