September 10, 2026 · Pediatric nephrology (Berlin, Germany) · DOI: 10.1007/s00467-026-07525-x

Adequacy of dialysis in children and adolescents: more than just Kt/V

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The authors investigate the evolving concept of dialysis adequacy in children and adolescents, questioning whether traditional measures like urea clearance (Kt/V) are sufficient. They highlight the importance of considering the removal of middle molecules, phosphorus control, and personalized treatment approaches that incorporate patient and family perspectives to improve clinical outcomes and quality of life. The study advocates for a more comprehensive and individualized approach to dialysis adequacy beyond conventional metrics.

Fabio Paglialonga, Hiren P Patel

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