The incidence and risk factors associated with severe acute kidney injury and operative mortality in neonates following cardiac surgery: a single-center experience

The authors aimed to investigate the incidence and risk factors for severe acute kidney injury (AKI) and operative mortality in neonates undergoing cardiac surgery, particularly comparing those with single ventricle physiology to those with biventricular physiology. Their study found a high prevalence of severe postoperative AKI (approximately 50%) and an operative mortality rate of 8% overall, with longer cardiopulmonary bypass time and delayed sternal closure identified as significant risk factors. The findings highlight the need for further research to develop predictive tools for AKI in this vulnerable population.