Impact of hormone therapy on mood in a real-world clinical setting: a retrospective observational study
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This study aimed to evaluate the impact of systemic hormone therapy (HT) on mood disturbances during the menopause transition in a real-world clinical setting. The results indicated a significant reduction in mood symptom scores among patients after initiating HT, particularly in those with severe baseline symptoms, suggesting that HT may be beneficial for improving mood in midlife women regardless of their psychiatric history or antidepressant use. The authors advocate for further research to explore HT's effects on mood in this population.
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