Incidence, medical therapy, and outcomes in heart failure with improved ejection fraction across guideline definitions

The authors aimed to assess the incidence of heart failure with improved ejection fraction (HFimpEF) across different guideline definitions and to evaluate the utilization of guideline-directed medical therapy (GDMT) and outcomes such as hospitalization or death among patients classified under each definition. They found that the prevalence of HFimpEF varied significantly based on the definition used, with a substantial proportion of patients still facing a high risk of clinical deterioration despite improvements in ejection fraction. This underscores the need for further research to optimize treatment strategies for these patients.