August 31, 2026 · American heart journal · DOI: 10.1016/j.ahj.2026.107594

Clinical and Economic Outcomes in Diagnostic-Naïve Medicare Fee-for-Service Beneficiaries Managed with Alert-Based Ambulatory Cardiac Monitors: the CAMELOT-ALERT Study

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The CAMELOT-ALERT Study aimed to compare the diagnostic yield and subsequent clinical and economic outcomes of mobile cardiac telemetry (MCT) versus ambulatory event monitoring (AEM) among arrhythmia diagnosis-naïve Medicare Fee-For-Service beneficiaries. The findings indicated that iRhythm MCT had a higher diagnostic yield and retesting rate compared to other MCT and AEM, but no significant differences were observed in overall clinical outcomes or costs. The authors suggest that further randomized trials are needed to clarify the performance differences between these monitoring platforms.

Pierantonio Russo, Jordan B Strom, Ramaa Nathan, Yang Song, Mostafa Shokoohi, Rod Passman, Matthew R Reynolds, Suneet Mittal

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