The science and conduct of surgical trials in gynecologic oncology: A practical framework

The authors aim to establish a practical framework for conducting surgical trials in gynecologic oncology, addressing the unique challenges these trials face compared to pharmacologic studies. They emphasize the importance of rigorous design and execution to minimize bias and enhance the credibility of findings, ultimately aiming to improve surgical practices and patient outcomes in the treatment of gynecologic cancers. The review outlines essential components for successful trial conduct, including eligibility criteria, randomization processes, and quality assurance measures.