August 6, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.07.035

Association between Corticosteroids and In-Hospital Mortality After Cardiac Arrest: A Multicenter Study Using the eICU Collaborative Research Database

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The authors aimed to investigate the association between corticosteroid administration and in-hospital mortality in adults who experienced cardiac arrest. Their study found that corticosteroids were linked to lower mortality rates, particularly in comatose patients and those with chronic obstructive pulmonary disease, while no significant benefits were observed in non-comatose patients. These findings highlight the need for phenotype-guided approaches in future research on corticosteroid use in this population.

Zhe Li, Lei Shi, Wan Chen, Guozheng Qiu, Wenlong Duan, Shengxin Chen, Zhe Zheng, Yao Zhou, Liwen Lyu

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