August 6, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.07.032

Impact of Low-density Lipoprotein Cholesterol Levels on Cardiovascular Risk in Chronic Kidney Disease: A Stage-specific Analysis

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The authors aimed to investigate the relationship between low-density lipoprotein cholesterol (LDL-C) levels and cardiovascular risk in patients with chronic kidney disease (CKD), stratified by kidney function. Their findings indicate that higher LDL-C levels are associated with increased cardiovascular event risk in CKD patients, particularly in those with end-stage kidney disease, suggesting the need for stage-specific LDL-C targets to optimize cardiovascular risk management in this population.

Nam Ju Heo, Kyungdo Han, Kyu-Na Lee, Jin-Hyung Jung, Tae-Min Rhee, Heesun Lee, Su-Yeon Choi

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