Photon-counting CT Extracellular Volume Fraction for Liver Fibrosis Assessment: Validation against MR Elastography and Histopathology
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The authors aimed to evaluate the feasibility of photon-counting CT (PCCT)-derived extracellular volume fraction (ECV) for staging liver fibrosis by comparing it with MR elastography-derived liver stiffness measurement (LSM) and using histopathology as the reference standard. Their findings demonstrated a strong correlation between ECV and LSM, with both methods showing equivalent diagnostic performance for liver fibrosis staging, indicating that PCCT-derived ECV is a clinically viable option for assessing liver fibrosis.
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